CD BioGlyco can provide one-stop custom services for glycoprotein-based vaccine development to meet customers' research needs. We have the confidence to be your essential research assistant in the field of glycobiology.
Rabies virus glycoprotein (RVGP) is the only antigen exposed on the surface of virus particles, which can induce the host to produce neutralizing antibodies. It is also the only viral component present in all new rabies vaccines. Many studies have expressed the immunogenic recombinant rabies virus glycoprotein (rRVGP) and related research on the similarity between it and natural RVGP in structure and in stimulating the body's immune response, providing research ideas for new rabies genetic engineering vaccines.
The hepatitis C virus (HCV) envelope glycoproteins E1 and E2 are critical in virus attachment and cell fusion, and the study of these proteins may provide valuable insights into their potential use in vaccines and antiviral strategies. The immunogenicity of E1 and E2 has led to various ongoing attempts to develop one or two envelope glycoproteins into vaccines.
Human herpesvirus 6B (HHV-6B) is a pathogen that infects most babies with fever and persistent sequelae, such as inflammation of the brain, but effective methods for preventing or treating HHV-6B infection have not been established. Some researchers have previously discovered the HHV-6B glycoprotein complex, which is an important factor in HHV-6B infection. They used this complex as a vaccine antigen and analyzed its effectiveness, hoping it will protect infants from the virus.
Fig 1. Hepatitis C E1 and E2 glycoprotein structures (Sepulveda-Crespo, D.; et al. 2020)
CD BioGlyco has developed highly specialized platforms and various systematic and innovative solutions for the design, expression or synthesis of glycoprotein vaccine candidates.
CD BioGlyco can provide an integrated solution from glycoprotein vaccine design, expression or synthesis, identification to quality control. For decades, we have won the trust of global scientists with high-quality products, services and technical support. In terms of vaccine development, our company has unique and advanced technology platforms. Excellent researchers and sophisticated instruments have become our powerful assistance, and we will assist you in your vaccine development process.
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