Long-chain Fatty Acid Analysis

CD BioGlyco is a leader in the field of Fatty Acid Analysis. Our scientists have been committed to the research of long-chain fatty acids (LCFAs), have accumulated rich experience, and achieved many results. We provide customers with analysis services of a variety of LCFAs.

Function of LCFAs

FAs are a class of carboxylic acid compounds, which are the main components of neutral fats, phospholipids, and glycolipids. According to different carbon chain lengths, FAs are classified into short-chain fatty acids (SCFAs), medium-chain fatty acids (MCFAs), LCFAs, and very long-chain fatty acids(VLCFAs). They convert each other in the process of life and play an important role in regulating various physiological and biological functions in the organism.

LCFAs refer to FAs with 14 to 24 carbon atoms, such as palmitic acid, stearic acid, oleic acid, and α-linolenic acid. They are found in most fats and oils, including olive oil, soybean oil, fish, nuts, avocado, and meat. LCFAs have two main functions in animals: 1) As a component of phospholipids and other complex lipids, they are an important structural component of cell membranes; 2) As a part of triacylglycerol, it is an important energy source for many tissues, and it also plays an important role in activating protein kinase C (PKC) and nuclear transcription factor pathways.

LCFAs play a role in cells through passive diffusion or carrier-mediated transport across the plasma membrane. The uptake of LCFAs by adipocytes plays an important role in maintaining lipid homeostasis. Adipocytes produce lipoprotein lipase, which acts on lipoprotein particles to produce LCFAs. After passing through endothelial cells, LCFAs bound to mesenchymal albumin interact with adipocytes to participate in a variety of metabolic processes.

LCFAs oxidation metabolism.Fig.1 LCFAs oxidation metabolism. (Li, 2015)

Our Services

LCFAs play a huge role in people's daily life, so scientists have been committed to the research of LCFAs. CD BioGlyco quantifies LCFAs by gas chromatography-mass spectrometry (GC-MS). Our analysis process is as follows:

Long-chain Fatty Acid Analysis

The LCFAs we analyzed include but are not limited to: palmitic acid, palmitoleic acid, heptadecanoic acid, stearic acid, oleic acid, linoleic acid, linolenic acid, eicosadienoic acid, arachidonic acid, eicosatrienoic acid, eicosapentaene acid, docosatrienoic acid, docosatetraenoic acid, and docosapentaenoic acid.

Advantages of Us

  • Good separation effect, high sensitivity, low detection limit, and good stability
  • Multiple quality control and strict proofreading of standard products
  • One-stop analysis solution and short experimental period

Applications

  • Study on the composition of medicinal plants
  • Metabolite kinetic analysis
  • Metabolic pathway analysis
  • Lipid metabolism research
  • Food and edible oil standard testing

CD BioGlyco has many successful cases in the analysis of LCFAs. Our one-stop analysis service has been greatly recognized internationally, and we will continue to explore to meet the analysis needs of customers in the field. If you are interested in our services, please feel free to contact us.

Reference:

  1. Ii, J.L.M.; Sun, A. Orphan drugs in development for long-chain fatty acid oxidation disorders: challenges and progress. Journal of Plant Pathology. 2015, 5: 33-41.
This service is for Research Use Only, not intended for any clinical use.

About Us

CD BioGlyco is a world-class biotechnology company with offices in many countries. Our products and services provide a viable option to what is otherwise available.

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