What Is C. albicans Chitin?

Chitin biosynthesis and cellular processing is a highly complex, multifaceted, and interconnected sequence of events. Chitin synthesis and degradation require tight enzymatic control to maintain homeostasis. Chitin synthase is a key enzyme in the chitin synthesis pathway, which uses UDP-N-acetylglucosamine (UDPGlcNAc) to produce chitin polymers, while chitinases degrade chitin. Chitin is a natural polysaccharide found in many organisms, including C. albicans. It is a linear polymer composed of N-acetylglucosamine molecules linked by β-1,4-glycosidic bonds. In C. albicans, chitin is mainly found in the cell wall and plays a role in providing strength and stability to the cell structure. Chitin has a variety of special chemical and biological properties, so it has a wide range of applications in medicine, bioscience, the food industry, agriculture, and materials science.

Fig.1 Events associated with chitin formation and degradation. (Elieh-Ali-Komi & Hamblin, 2016)

C. albicans Chitin Production Services at CD BioGlyco

• Provision of C. albicans strains

CD BioGlyco provides high-yielding C. albicans chitin strains for antigen and vaccine development projects for further research as antigens or vectors.

• Chitin grooming services

CD BioGlyco provides chitin modification services to improve the stability, immune activity, and biological activity of the antigen.

• Chemical modification

CD BioGlyco introduces specific functional groups or chemical groups through chemical reactions (acetylation, deacetylation, sulfonation, carboxylation, etc.) to change the properties of chitin.

• Surface modification

CD BioGlyco introduces specific molecules, polymers, or functional groups on the surface of chitin to change its surface properties and interaction characteristics. These modifications include polyethylene glycol modification, biotinylation, fluorescent labeling, etc.

• Functional modification

CD BioGlyco connects molecules with specific functions to chitin molecules to give them specific biological activities or application functions. These modifications include drug modification, dye modification, antibacterial modification, etc.

• Immunomodification

CD BioGlyco has a comprehensive Carbohydrate-based Adjuvant Development platform. We conduct conjugation chemical reactions or special immune modification technology on chitin to combine it with antigens or antibodies to improve its immunogenicity or be used in vaccine research.

• Enzyme modification

CD BioGlyco uses enzymatic reactions or other biocatalytic methods to perform specific biological modifications on chitin. These modifications include glycosylation, deacetylation, branching, etc.

• Production and optimization of chitin

By optimizing the chitin production process, CD BioGlyco increases the production of chitin in C. albicans to meet the needs of large-scale vaccine preparation.

• Purification and extraction of chitin

CD BioGlyco develops and optimizes chitin purification and extraction methods to obtain high-purity chitin for antigen preparation.

• Chitin analysis services

CD BioGlyco provides precise analysis of C. albicans chitin, including testing and verifying parameters such as purity, stability, and integrity of samples.

Fig.2 C. albicanschitin production services. (CD BioGlyco)

Applications

• Pharmaceutical field: C. albicans chitin is used as a carrier in drug delivery systems to control drug release and enhance drug stability.
• Food industry: C. albicans chitin is used as a stabilizer, thickener, emulsifier, and preservative to improve food texture, extend shelf life, and increase the nutritional value of food.
• Agriculture: C. albicans chitin is used as a plant growth regulator to promote plant growth and increase yields.
• Materials science: C. albicans chitin has potential applications in materials science, which are applied to prepare biodegradable materials, cellulose-based composites, and bioplastics to replace traditional petrochemical materials.

Advantages

• Strong R&D capabilities: CD BioGlyco actively carries out technological innovation and R&D work to ensure the provision of high-quality C. albicans chitin production process services.
• Diversified product selection: CD BioGlyco provides mature C. albicans chitin products of different specifications to meet the diverse needs of clients.
• Fast delivery: CD BioGlyco efficiently completes production tasks and delivers the required C. albicans chitin products on time.

CDBioGlyco has the advanced Glyco™ Vaccine Development Platform, and we provide custom C. albicans chitin production services to meet specific specifications and magnitude requirements. If you need efficient and high-quality product services, we are your best choice. Please feel free to contact us in time to obtain detailed service content.

References

1. Elieh-Ali-Komi, D.; Hamblin, M.R. Chitin and chitosan: production and application of versatile biomedical nanomaterials. International Journal of Advanced Research. 2016, 4(3): 411.
2. Bowman, S.M.; Free, S.J. The structure and synthesis of the fungal cell wall. Bioessays. 2006, 28(8): 799-808.