Properties
Description
DOTA-chelated chondroitin sulfate (DOTA-CS) incorporates tetraazacyclododecane tetraacetic acid for radiometal coordination, enabling diagnostic imaging applications.
Glycan Name
Chondroitin sulfate
Glycan Structure
The glycan structure of chondroitin sulfate (CS) is a sulfated glycosaminoglycan (GAG) composed of repeating disaccharide units. Each unit consists of:
N-acetyl-D-galactosamine (GalNAc) (β1→4 linked)
D-glucuronic acid (GlcA) (β1→141 linked)
Source
Chemical synthesis
Impurities
No visible impurities to the naked eye.
Solubility
This product is soluble in most organic solvents, such as DCM, DMF, DMSO, and THF, and exhibits excellent solubility in water.
Identity
Confirmed by NMR.
Applications
Chondroitin sulfate-1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid can be used for its potential to design macrocyclic chelators for heavy metal ion binding assays.