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O-GlcNAcase inhibitor, Thiamet G, Purity ≥98%

Cat. No.: X24-09-YM796

O-GlcNAcase inhibitor, Thiamet G, Purity ≥98%

Synonym: 1009816-48-1; O-GlcNAcase inhibitor

  • CAS Number: 1009816-48-1
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Product Size
5 mg; 10 mg; 25 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Thiamet G, soluble in DMSO, water, and ethanol, is a potent, selective O-GlcNAcase inhibitor with Kiof 21 nM while exhibiting 37,000-fold selectivity over human lysosomal-hexosaminidase. The molecular weight of the compound is 248.3, and its molecular formula is C9H16N2O4S. It targets the O-GlcNAcase.
Molecular Weight
248.3
Molecular Formula
C9H16N2O4S
Targets
O-GlcNAcase
Form
Lyophilized powder
Purity
≥98%
Impurities
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.
Solubility
In vitro: DMSO: 47 mg/mL (189.28 mM); Water: 47 mg/mL (189.28 mM); Ethanol: 11 mg/mL (44.29 mM); In vivo: Saline, 28 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
Thiamet G can be studied extensively for its potential therapeutic applications in the treatment of metabolic diseases and neurodegenerative disorders by modulating O-GlcNAcylation levels, which can influence cellular signaling and function.
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