Properties
Description
Isothiocyanate-activated chondroitin sulfate (NCS-CS) serves as amine-reactive intermediate through thiourea bond formation for antibody conjugation.
Glycan Name
Chondroitin sulfate
Glycan Structure
The glycan structure of chondroitin sulfate (CS) is a sulfated glycosaminoglycan (GAG) composed of repeating disaccharide units. Each unit consists of:
N-acetyl-D-galactosamine (GalNAc) (β1→4 linked)
D-glucuronic acid (GlcA) (β1→142 linked)
Source
Chemical synthesis
Functional Group
Isothiocyanate
Impurities
No visible impurities to the naked eye.
Solubility
This product is soluble in most organic solvents, such as DCM, DMF, DMSO, and THF, and exhibits excellent solubility in water.
Identity
Confirmed by NMR.
Applications
Chondroitin sulfate-isothiocyanate can be used for its potential to explore isothiocyanate coupling mechanisms in peptide-polymer conjugation.
