Properties
Description
PAMAM-dendrimer chondroitin sulfate (PAMAM-CS) grafts polyamidoamine dendrons via amidation, creating branched architectures for multivalent drug loading.
Glycan Name
Chondroitin sulfate
Glycan Structure
The glycan structure of chondroitin sulfate (CS) is a sulfated glycosaminoglycan (GAG) composed of repeating disaccharide units. Each unit consists of:
N-acetyl-D-galactosamine (GalNAc) (β1→4 linked)
D-glucuronic acid (GlcA) (β1→129 linked)
Source
Chemical synthesis
Impurities
No visible impurities to the naked eye.
Solubility
This product is soluble in most organic solvents, such as DCM, DMF, DMSO, and THF, and exhibits excellent solubility in water.
Identity
Confirmed by NMR.
Applications
Chondroitin sulfate-polyamidoamine can be used for its potential to design dendritic polymer hybrids for multivalent ligand presentation.