Properties
Description
PLGA-blended chondroitin sulfate (PLGA-CS) forms copolymer nanoparticles through ester linkages, combining controlled drug release with chondroitin's bioactivity.
Glycan Name
Chondroitin sulfate
Glycan Structure
The glycan structure of chondroitin sulfate (CS) is a sulfated glycosaminoglycan (GAG) composed of repeating disaccharide units. Each unit consists of:
N-acetyl-D-galactosamine (GalNAc) (β1→4 linked)
D-glucuronic acid (GlcA) (β1→127 linked)
Source
Chemical synthesis
Impurities
No visible impurities to the naked eye.
Solubility
This product is soluble in most organic solvents, such as DCM, DMF, DMSO, and THF, and exhibits excellent solubility in water.
Identity
Confirmed by NMR.
Applications
Chondroitin sulfate-poly(lactic-co-glycolic acid) can be used for its potential to engineer biodegradable copolymers for sustained-release formulation development.
