SGK1 inhibitor, GSK-650394, Purity ≥98%

Synonym: 890842-28-1; GSK 650394; GSK650394; 2-Cyclopentyl-4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid; SGK1 inhibitor

MDL: MFCD12828779
CAS Number: 890842-28-1
Compound CID: 25022668

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

MSDS

Properties

Description

GSK-650394, soluble in DMSO and insoluble in water and ethanol, is a glucocorticoid- and serum-regulated kinase 1 (SGK1) inhibitor. The molecular weight of the compound is 382.45, and its molecular formula is C₂₅H₂₂N₂O₂. It targets the SGK1 and SGK2.

Molecular Weight

382.45

Molecular Formula

C₂₅H₂₂N₂O₂

Targets

Form

Lyophilized powder

Purity

Impurities

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.

Solubility

In vitro: DMSO: 72 mg/mL (188.25 mM); Water: insoluble; Ethanol: insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

GSK-650394 can be studied extensively for its potential therapeutic applications in the treatment of cancer and metabolic disorders, by modulating cellular survival and growth pathways.