Properties
Description
Tretinoin-linked chondroitin sulfate (tretinoin-CS) covalently tethers the retinoid molecule through pH-sensitive bonds, merging chondroitin's tissue-regenerative properties with tretinoin's cellular differentiation effects.
Glycan Name
Chondroitin sulfate
Glycan Structure
The glycan structure of chondroitin sulfate (CS) is a sulfated glycosaminoglycan (GAG) composed of repeating disaccharide units. Each unit consists of:
N-acetyl-D-galactosamine (GalNAc) (β1→4 linked)
D-glucuronic acid (GlcA) (β1→108 linked)
Source
Chemical synthesis
Functional Group
Tretinoin
Impurities
No visible impurities to the naked eye.
Solubility
This product is soluble in most organic solvents, such as DCM, DMF, DMSO, and THF, and exhibits excellent solubility in water.
Identity
Confirmed by NMR.
Applications
Chondroitin sulfate-tretinoin can be used for its potential to investigate retinoid delivery efficiency in dermal regeneration models.