Properties
Description
Iodoacetate-PEG-mannose hybrids feature halogenated acetate groups covalently linked via hydrophilic polymer bridges to carbohydrate backbones, enabling thiol-selective alkylation reactions in bioconjugation processes.
Source
Chemical synthesis
Impurities
No visible impurities to the naked eye.
Solubility
This product is soluble in most organic solvents, such as DCM, DMF, DMSO, and THF, and exhibits excellent solubility in water.
Identity
Confirmed by NMR.
Applications
Mannose-PEG-iodoacetate can be used for its potential to alkylate cysteine residues for irreversible protein conjugation.