Properties
Description
Raltitrexed-PEG-mannose hybrids integrate thymidylate synthase inhibitors conjugated through hydrophilic spacers to carbohydrate units, improving chemotherapeutic delivery to hepatic tissues.
Source
Chemical synthesis
Impurities
No visible impurities to the naked eye.
Solubility
This product is soluble in most organic solvents, such as DCM, DMF, DMSO, and THF, and exhibits excellent solubility in water.
Identity
Confirmed by NMR.
Applications
Mannose-PEG-raltitrexed can be used for its potential to study thymidylate synthase inhibition in colorectal cancer models.