Properties
Description
This well-defined (≥95% pure) bioconjugate comprises PAE and lactosyl connected by a 1 kDa polyethylene glycol (PEG) spacer, enabling research on biodegradable cationic polymers with carbohydrate ligands for cell-specific uptake.
Molecular Weight
PEG 1 kDa
Source
Chemical synthesis
Solubility
PAE-PEG-lactosyl is soluble in a wide range of organic solvents, such as DCM, DMF, and DMSO, and shows excellent solubility in water.
Identity
Confirmed by NMR.
Applications
PAE conjugated to lactosyl with a 1 kDa PEG spacer can be used to examine the influence of PEGylation on the cytotoxicity and serum stability of carbohydrate-modified PAE gene delivery vectors.