Properties
Description
This well-defined (≥95% pure) bioconjugate comprises PAMAM dendrimer and lactosyl connected by a 1 kDa polyethylene glycol (PEG) spacer, enabling research on dendrimers with carbohydrate targeting moieties.
Molecular Weight
PEG 1 kDa
Source
Chemical synthesis
Solubility
PAMAM-PEG-lactosyl is soluble in a wide range of organic solvents, such as DCM, DMF, and DMSO, and shows excellent solubility in water.
Identity
Confirmed by NMR.
Applications
PAMAM conjugated to lactosyl with a 1 kDa PEG spacer can be used to examine the effect of PEGylation on the colloidal stability and aggregation behavior of carbohydrate-modified dendrimers in biological buffers.