Properties
Description
This well-defined (≥95% pure) bioconjugate comprises PLGA and lactosyl connected by a 1 kDa polyethylene glycol (PEG) spacer, enabling research on biodegradable nanoparticles with carbohydrate ligands for cell-specific uptake.
Molecular Weight
PEG 1 kDa
Source
Chemical synthesis
Solubility
PLGA-PEG-lactosyl is soluble in a wide range of organic solvents, such as DCM, DMF, and DMSO, and shows excellent solubility in water.
Identity
Confirmed by NMR.
Applications
PLGA conjugated to lactosyl with a 1 kDa PEG spacer can be used to study the effect of increased PEG chain length on the degradation rate and drug release profile of carbohydrate-targeted nanoparticles.