Properties
Description
This high-purity (≥95%) reagent features poly(N-isopropylacrylamide) (PNIPAAm), a thermoresponsive polymer, conjugated to lactosyl via a 350 Da polyethylene glycol (PEG) spacer for studies involving temperature-sensitive targeting.
Molecular Weight
PEG 350 Da
Source
Chemical synthesis
Solubility
PNIPAAm-PEG-lactosyl is soluble in a wide range of organic solvents, such as DCM, DMF, and DMSO, and shows excellent solubility in water.
Identity
Confirmed by NMR.
Applications
PNIPAAm (poly(N-isopropylacrylamide)) conjugated to lactosyl with a 350 Da PEG spacer can be used to develop thermo-responsive nanoparticles with carbohydrate targeting for controlled drug release triggered by temperature changes near cells.