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CDK inhibitor LY2835219 methanesulfonate, Purity ≥98%
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Cat. No.: X24-05-ZQ780

CDK inhibitor LY2835219 methanesulfonate, Purity ≥98%

Synonym: 1231930-82-7; Abemaciclib; CDK inhibitor

  • CAS Number: 1231930-82-7
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Product Size
5 mg; 10 mg; 50 mg
Price
Datasheet
MSDS
Properties
Description
LY2835219 methanesulfonate, soluble in DMSO, water and ethanol, is an CDK kinase inhibitor that disrupts cell division processes. It targets CDK1/cyclinB1, CDK2/cyclinE, Cdk4/cyclin D1, and Cdk5/p25.
Molecular Weight
602.7
Molecular Formula
C27H32F2N8.CH4O3S
Targets
CDK1/cyclinB1: 1627 nM; CDK2/cyclinE: 504 nM; Cdk4/cyclin D1: 2 nM; Cdk5/p25: 355 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 81 mg/mL (134.39 mM); Water: 97 mg/mL (160.94 mM); Ethanol: 23 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
LY2835219 methanesulfonate (Abemaciclib) can be used to explore its effects as a selective CDK4/6 inhibitor in cancer cell proliferation.
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