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CDK inhibitor LY2835219, Purity ≥98%
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Cat. No.: X24-05-ZQ748

CDK inhibitor LY2835219, Purity ≥98%

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Synonym: 1231929-97-7; LY 2835219; LY-2835219; Abemaciclib; CDK inhibitor

  • CAS Number: 1231929-97-7
  • Compound CID: 46220502
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Product Size
5 mg; 10 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
LY2835219, soluble in DMSO and ethanol and insoluble in water, is an CDK kinase inhibitor that disrupts cell division processes. It targets CDK1/cyclinB1, CDK2/cyclinE, Cdk4/cyclin D1, and Cdk5/p25.
Molecular Weight
506.59
Molecular Formula
C27H32F2N8
Targets
CDK1/cyclinB1: 1627 nM; CDK2/cyclinE: 504 nM; Cdk4/cyclin D1: 2 nM; Cdk5/p25: 355 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 6 mg/mL (11.84 mM); Water: Insoluble; Ethanol: 8 mg/mL (15.79 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
LY2835219 (Abemaciclib) can be used to study the targeted inhibition of CDK4/6 in cancer therapies.
Publications
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