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CDK inhibitor PD 0332991 HCl, Purity ≥98%
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Cat. No.: X24-05-ZQ723

CDK inhibitor PD 0332991 HCl, Purity ≥98%

Synonym: 827022-32-2; Palbociclib; CDK inhibitor

  • CAS Number: 827022-32-2
  • Compound CID: 11431660
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Product Size
5 mg; 10 mg; 25 mg; 50 mg
Price
Datasheet
MSDS
Properties
Description
PD 0332991 HCl, soluble in warmed DMSO and water and insoluble in ethanol, is an CDK kinase inhibitor that disrupts cell division processes. It targets CDK4/CyclinD1, CDK6/CyclinD2, AMPK, and c-Src.
Molecular Weight
484
Molecular Formula
C24H29N7O2.HCl
Targets
CDK4/CyclinD1: 11 nM; CDK6/CyclinD2: 15 nM; AMPK: >10 μM; c-Src: >10 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
Warmed DMSO: 3 mg/mL (6.19 mM); Water: 30 mg/mL (61.98 mM); Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
PD0332991 HCl is used to explore its selective inhibition of CDK4/6 and its implications for treating cancers driven by CDK4/6 activity.
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