PD 0332991 HCl, soluble in warmed DMSO and water and insoluble in ethanol, is an CDK kinase inhibitor that disrupts cell division processes. It targets CDK4/CyclinD1, CDK6/CyclinD2, AMPK, and c-Src.
PD0332991 HCl is used to explore its selective inhibition of CDK4/6 and its implications for treating cancers driven by CDK4/6 activity.
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