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CDK inhibitor Purvalanol A, Purity ≥98%
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Cat. No.: X24-05-ZQ774

CDK inhibitor Purvalanol A, Purity ≥98%

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Synonym: 212844-53-6; NG-60; CDK inhibitor

  • CAS Number: 212844-53-6
  • Compound CID: 456214
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Product Size
10 mg; 25 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Purvalanol A, soluble in warmed DMSO and warmed ethanol and insoluble in water, is an CDK kinase inhibitor that disrupts cell division processes. It targets Cdc2/CyclinB, CDK2/CyclinA, CDK2/CyclinE, CDK4/CyclinD1.
Molecular Weight
388.89
Molecular Formula
C19H25ClN6O
Targets
Cdc2/CyclinB: 4 nM; CDK2/CyclinA: 70 nM; CDK2/CyclinE: 35 nM; CDK4/CyclinD1: 850 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
Warmed DMSO: 53 mg/mL (136.28 mM); Water: Insoluble; Warmed ethanol: 11 mg/mL (28.28 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
Purvalanol A can be employed to investigate the inhibition of CDKs and its impact on cell cycle regulation.
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