FITC-dextran, a water-soluble yellow powder, consists of a fluorescein moiety anchored stably by a thiocarbamoyl linkage without causing any depolymerization of the dextran. This compound exhibits its highest intensity at a pH greater than 8, reaching excitation and emission maximums of 490-495 nm and 520 ± 12 nm, respectively. FITC-dextran is a high-quality product with a molecular weight of 400,000-600,000 and a degree of substitution of 0.001-0.020.
Molecular Weight
400,000-600,000
Label
FITC
Degree of Substitution
0.1-2%
Form
Yellow powder
Solubility
FITC-dextran dissolves readily in water.
Identity
Confirmed by NMR/HPLC/MS.
Applications
FITC-dextran with a molecular weight of 400,000-600,000 and DS of 0.001-0.020 can be used for the study of permeability, microcirculation, as well as the delivery of drugs while serving as a significant marker for molecular size and a sensitive pH indicator in various biological and chemical settings.
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