Properties
                                        
                            Description
                            NSC87877 disodium salt, soluble in DMSO and water and insoluble in ethanol, blocks the activity of enzymes that remove phosphate groups from tyrosine residues in proteins, affecting signal transduction and cellular processes. It targets SHP-1 and SHP-2.
                         
                                                                            
                                                            
                            Molecular Formula
                            C19H13N3O7S2.2Na
                         
                                                                                                                                            
                            Targets
                            SHP-1: 355 nM; SHP-2: 318 nM
                         
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
                                                            
                                                                                                                                                                            
                            Solubility
                            DMSO: 85 mg/mL (168.84 mM); Water: 85 mg/mL (168.84 mM); Ethanol: Insoluble
                         
                                                            
                            Identity
                            Confirmed by NMR/HPLC/MS.
                         
                                                                                                                                                            
                            Applications
                            NSC87877 disodium salt can be used to inhibit SHP2 and SHP1 phosphatase activities in various cellular signaling studies.