June 2, 2026
Automated Chemoenzymatic Glycan Synthesis: A Nap-Tag Breakthrough
Almost all eukaryotic cell surfaces and secreted proteins are modified by complex carbohydrates, known as glycans, which regulate processes ranging from protein folding and cell–cell communication to immune responses and fertilization. Aberrant glycosylation is linked to inflammation, autoimmunity, allergy, and cancer. Diverse, well-defined glycan collections are essential for studying glycan-binding proteins, serving as reference standards […]
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