Amifostine hydrate, insoluble in DMSO and ethanol and soluble in water, is the first approved radioprotective compound. The molecular weight of the compound is 268.27, and its molecular formula is C5H15N2O3PS·3H2O.
Molecular Weight
268.27
Molecular Formula
C5H15N2O3PS·3H2O
Form
Lyophilized powder
Purity
≥98%
Impurities
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.
Solubility
In vitro: DMSO: insoluble; Water (warmed): 39 mg/mL (145.37 mM); Ethanol: insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
Amifostine hydrate plays a key role in protecting normal tissues from the toxic effects of chemotherapy and radiation.
Publications
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Publications
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