Properties
Description
Azaguanine-8, soluble in DMSO and insoluble in water and ethanol, is a purine analog showing antineoplastic activity by competing with guanine in the metabolism. The molecular weight of the compound is 152.11, and its molecular formula is C4H4N6O.
Molecular Formula
C4H4N6O
Impurities
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.
Solubility
In vitro: DMSO: 6 mg/mL (39.44 mM); Water: insoluble; Ethanol: insoluble; In vivo: 5% DMSO + 45% PEG 300 + ddH2O, 1 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
Azaguanine-8 plays a key role in targeting tumors that are sensitive to such metabolic disruptions.