Azide-chondroitin sulfate click chemistry handle is introduced through diazo transfer reactions, enabling copper-catalyzed cycloaddition with alkyne-functionalized molecules.
Glycan Name
Chondroitin sulfate
Glycan Structure
The glycan structure of chondroitin sulfate (CS) is a sulfated glycosaminoglycan (GAG) composed of repeating disaccharide units. Each unit consists of:
N-acetyl-D-galactosamine (GalNAc) (β1→4 linked)
D-glucuronic acid (GlcA) (β1→102 linked)
Source
Chemical synthesis
Functional Group
Azide
Form
Solid or powder
Purity
≥95%
Impurities
No visible impurities to the naked eye.
Solubility
This product is soluble in most organic solvents, such as DCM, DMF, DMSO, and THF, and exhibits excellent solubility in water.
Identity
Confirmed by NMR.
Applications
Chondroitin sulfate-N3 can be used for its potential to study histidine protonation effects on endosomal membrane disruption.
Publications
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Publications
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