Properties
Description
Ciprofloxacin-chondroitin sulfate antibacterial hybrid links the fluoroquinolone via 尾-thioether bonds, maintaining bactericidal activity while improving chondroitin-mediated mucosal retention.
Glycan Name
Chondroitin sulfate
Glycan Structure
The glycan structure of chondroitin sulfate (CS) is a sulfated glycosaminoglycan (GAG) composed of repeating disaccharide units. Each unit consists of:
N-acetyl-D-galactosamine (GalNAc) (β1→4 linked)
D-glucuronic acid (GlcA) (β1→35 linked)
Source
Chemical synthesis
Functional Group
Ciprofloxacin
Impurities
No visible impurities to the naked eye.
Solubility
This product is soluble in most organic solvents, such as DCM, DMF, DMSO, and THF, and exhibits excellent solubility in water.
Identity
Confirmed by NMR.
Applications
Chondroitin sulfate-ciprofloxacin can be used for its potential to engineer fluoroquinolone conjugates for biofilm penetration assays.
