Properties
Description
Cisplatin-chondroitin sulfate coordination complex utilizes platinum's ligand-binding properties to chelate the drug molecule within chondroitin's polymeric architecture, enhancing tumor accumulation.
Glycan Name
Chondroitin sulfate
Glycan Structure
The glycan structure of chondroitin sulfate (CS) is a sulfated glycosaminoglycan (GAG) composed of repeating disaccharide units. Each unit consists of:
N-acetyl-D-galactosamine (GalNAc) (β1→4 linked)
D-glucuronic acid (GlcA) (β1→15 linked)
Source
Chemical synthesis
Functional Group
Cisplatin
Impurities
No visible impurities to the naked eye.
Solubility
This product is soluble in most organic solvents, such as DCM, DMF, DMSO, and THF, and exhibits excellent solubility in water.
Identity
Confirmed by NMR.
Applications
Chondroitin sulfate-cisplatin can be used for its potential to evaluate platinum drug delivery efficiency in solid tumor microenvironments.
