Properties
Description
cRGD peptide-chondroitin sulfate targeting conjugate employs heterobifunctional PEG spacers to optimize integrin-binding presentation while maintaining chondroitin's inherent biodistribution.
Glycan Name
Chondroitin sulfate
Glycan Structure
The glycan structure of chondroitin sulfate (CS) is a sulfated glycosaminoglycan (GAG) composed of repeating disaccharide units. Each unit consists of:
N-acetyl-D-galactosamine (GalNAc) (β1→4 linked)
D-glucuronic acid (GlcA) (β1→28 linked)
Source
Chemical synthesis
Impurities
No visible impurities to the naked eye.
Solubility
This product is soluble in most organic solvents, such as DCM, DMF, DMSO, and THF, and exhibits excellent solubility in water.
Identity
Confirmed by NMR.
Applications
Chondroitin sulfate-cRGD peptide can be used for its potential to enhance cyclic peptide targeting for angiogenic tumor regions.
