DMT-2'-O-Methylguanosine phosphoramidite is a protected 2'-O-methylguanine phosphamide compound, which is often used for ligation and assembly in nucleic acid synthesis. The DMT (N,N'-dimethylfluorophenyl) group can be used to protect the 5' end of the nucleotide.
Molecular Weight
799.85
Molecular Formula
C41H50N7O8P
Form
Solid
Purity
≥95.0%
Applications
DMT-2'-O-Methylguanosine phosphoramidite is mainly used in the synthesis and modification of RNA to enhance its stability and resistance to nucleases, it is often employed in RNA interference, gene regulation, and antiviral research.
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Publications
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