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HDAC inhibitor Abexinostat, Purity ≥98%
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Cat. No.: X23-10-ZQ310

HDAC inhibitor Abexinostat, Purity ≥98%

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Synonym: 783355-60-2; ABEXINOSTAT; PCI-24781; PCI 24781; CRA-024781; CRA 024781; CRA-02478; HDAC inhibitor

  • MDL: MFCD10565969
  • CAS Number: 783355-60-2
  • Compound CID: 11749858
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Abexinostat, soluble in DMSO and insoluble in ethanol and water, induces DNA damage and the inhibition of DNA repair processes. It targets HDAC1, HDAC10, HDAC2, HDAC3/SMRT, HDAC6, and HDAC8.
Molecular Weight
397.4
Molecular Formula
C21H23N3O5
Targets
HDAC1: 7 nM (Ki); HDAC10: 24 nM; HDAC2: 19 nM (Ki); HDAC3/SMRT: 8.2 nM (Ki); HDAC6: 17 nM (Ki); HDAC8
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 72 mg/mL (181.16 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
Abexinostat is used in research to explore its potential as a pan-HDAC inhibitor for cancer treatment.
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