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HDAC inhibitor HPOB, Purity ≥98%
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Cat. No.: X23-10-ZQ289

HDAC inhibitor HPOB, Purity ≥98%

Synonym: 1429651-50-2; HPOB; N-Hydroxy-4-(2-((2-hydroxyethyl)(phenyl)amino)-2-oxoethyl)benzamide; N-Hydroxy-4-[2-[N-(2-hydroxyethyl)anilino]-2-oxoethyl]benzamide; 4-[2-[2-Hydroxyethyl(Phenyl)amino]-2-oxidanylidene-ethyl]-~{n}-Oxidanyl-Benzamide; 4-[(Hydroxyamino)carbonyl]-N-(2-hydroxyethyl)-N-phenylbenzeneacetamide; HDAC inhibitor

  • CAS Number: 1429651-50-2
  • Compound CID: 71532921
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Product Size
10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
MSDS
Properties
Description
HPOB, soluble in DMSO and warmed ethanol and insoluble in water, induces DNA damage and the inhibition of DNA repair processes. It targets HDAC3, HDAC8, HDAC1, HDAC10, HDAC11, HDAC2, HDAC4, HDAC5, HDAC6, and HDAC7.
Molecular Weight
314.3
Molecular Formula
C17H18N2O4
Targets
HDAC3: 1.7 μM; HDAC8: 2.8 μM; HDAC1: 2.9 μM; HDAC10: 3.0 μM; HDAC11: 3.0 μM; HDAC2: 4.4 μM; HDAC4: >10 μM; HDAC5: >10 μM; HDAC6: 56 nM; HDAC7: >10 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 60 mg/mL (190.87 mM); Water: Insoluble; Warmed ethanol: 37 mg/mL (117.7 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
HPOB is investigated for its role as an HDAC6 inhibitor, providing insights into its potential therapeutic use in cancer and neurodegenerative diseases.
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