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HDAC inhibitor TMP 269, Purity ≥98%
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Cat. No.: X23-10-ZQ342

HDAC inhibitor TMP 269, Purity ≥98%

Synonym: 1314890-29-3; TMP269; N-((4-(4-Phenylthiazol-2-yl)tetrahydro-2H-pyran-4-yl)methyl)-3-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzamide; TMP-269; N-{[4-(4-Phenyl-1,3-thiazol-2-yl)oxan-4-yl]methyl}-3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide; HDAC inhibitor

  • MDL: MFCD26522023
  • CAS Number: 1314890-29-3
  • Compound CID: 53344908
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
MSDS
Properties
Description
TMP 269, soluble in DMSO and warmed ethanol and insoluble in water, induces DNA damage and the inhibition of DNA repair processes. It targets HDAC3 and HDAC1.
Molecular Weight
514.52
Molecular Formula
C25H21F3N4O3S
Targets
HDAC3: 5 nM (Ki); HDAC1: 32 nM (Ki)
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 89 mg/mL (172.97 mM); Water: Insoluble; Warmed ethanol: 2 mg/mL (3.88 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
TMP 269 is utilized to investigate the inhibition of specific HDAC subclasses, particularly class IIb HDACs, in cellular differentiation and disease models.
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