Histidine-chondroitin sulfate pH-responsive conjugate leverages imidazole's buffering capacity to create charge-switchable polymers for smart drug delivery.
Glycan Name
Chondroitin sulfate
Glycan Structure
The glycan structure of chondroitin sulfate (CS) is a sulfated glycosaminoglycan (GAG) composed of repeating disaccharide units. Each unit consists of:
N-acetyl-D-galactosamine (GalNAc) (β1→4 linked)
D-glucuronic acid (GlcA) (β1→56 linked)
Source
Chemical synthesis
Functional Group
His
Form
Solid or powder
Purity
≥95%
Impurities
No visible impurities to the naked eye.
Solubility
This product is soluble in most organic solvents, such as DCM, DMF, DMSO, and THF, and exhibits excellent solubility in water.
Identity
Confirmed by NMR.
Applications
Chondroitin sulfate-His can be used for its potential to analyze cell-penetrating peptide behavior in mitochondrial targeting.
Publications
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Publications
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