Properties
Description
ML-281, soluble in DMSO and ethanol and insoluble in water, is a potent and selective STK33 inhibitor. The molecular weight of the compound is 389.47, and its molecular formula is C22H19N3O2S.
Molecular Formula
C22H19N3O2S
Impurities
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.
Solubility
In vitro: DMSO: 69 mg/mL (177.16 mM); Water: insoluble; Ethanol: 3 mg/mL (7.7 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
ML-281 can be studied extensively for its potential therapeutic applications in the treatment of inflammatory diseases such as chronic obstructive pulmonary disease (COPD) and asthma, as well as various neurodegenerative disorders, by modulating cyclic AMP levels.
