PDHK1 inhibitor, AZD 7545, Purity ≥98%

Synonym: 252017-04-2; AZD-7545; AZD7545; 4-[3-Chloro-4-[[(2R)-3,3,3-trifluoro-2-hydroxy-2-methylpropanoyl]amino]phenyl]sulfonyl-N,N-dimethylbenzamide; PDHK1 inhibitor

MDL: MFCD25976792
CAS Number: 252017-04-2
Compound CID: 16741245

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

MSDS

Properties

Description

AZD 7545, soluble in DMSO and ethanol and insoluble in water, is a novel, selective small-molecule inhibitor of PDHK2. The molecular weight of the compound is 478.87, and its molecular formula is C₁₉H₁₈ClF₃N₂O₅S. It targets the PDHK1 and PDHK2.

Molecular Weight

478.87

Molecular Formula

C₁₉H₁₈ClF₃N₂O₅S

Targets

PDHK1

Form

Lyophilized powder

Purity

Impurities

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.

Solubility

In vitro: DMSO: 92 mg/mL (192.12 mM); Water: insoluble; Ethanol: 92 mg/mL (192.12 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

AZD 7545 can be used for its ability to decrease fatty acid synthesis and increase fatty acid oxidation, improving metabolic health.