Properties
Description
PNIPAAm-grafted chondroitin sulfate (PNIPAAm-CS) combines thermoresponsive poly(N-isopropylacrylamide) chains with the polysaccharide via covalent linkages, leveraging both components' adaptive properties for temperature-sensitive applications.
Glycan Name
Chondroitin sulfate
Glycan Structure
The glycan structure of chondroitin sulfate (CS) is a sulfated glycosaminoglycan (GAG) composed of repeating disaccharide units. Each unit consists of:
N-acetyl-D-galactosamine (GalNAc) (β1→4 linked)
D-glucuronic acid (GlcA) (β1→105 linked)
Source
Chemical synthesis
Impurities
No visible impurities to the naked eye.
Solubility
This product is soluble in most organic solvents, such as DCM, DMF, DMSO, and THF, and exhibits excellent solubility in water.
Identity
Confirmed by NMR.
Applications
Chondroitin sulfate-poly(N-isopropylacrylamide) can be used for its potential to design thermoresponsive hydrogels for studying temperature-dependent drug release kinetics.
