Sulfadimethoxine-chondroitin sulfate antimicrobial polymer links the sulfonamide through diazonium salt coupling, maintaining antibacterial efficacy while enhancing solubility.
Glycan Name
Chondroitin sulfate
Glycan Structure
The glycan structure of chondroitin sulfate (CS) is a sulfated glycosaminoglycan (GAG) composed of repeating disaccharide units. Each unit consists of:
N-acetyl-D-galactosamine (GalNAc) (β1→4 linked)
D-glucuronic acid (GlcA) (β1→45 linked)
Source
Chemical synthesis
Functional Group
Sulfadimethoxine
Form
Solid or powder
Purity
≥95%
Impurities
No visible impurities to the naked eye.
Solubility
This product is soluble in most organic solvents, such as DCM, DMF, DMSO, and THF, and exhibits excellent solubility in water.
Identity
Confirmed by NMR.
Applications
Chondroitin sulfate-sulfadimethoxine can be used for its potential to engineer nitroimidazole carriers for anaerobic microbial targeting.
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