Properties
Description
Tetrazine-chondroitin sulfate inverse electron-demand Diels-Alder partner is prepared through strained diene conjugation, enabling rapid bioorthogonal ligation with trans-cyclooctene moieties.
Glycan Name
Chondroitin sulfate
Glycan Structure
The glycan structure of chondroitin sulfate (CS) is a sulfated glycosaminoglycan (GAG) composed of repeating disaccharide units. Each unit consists of:
N-acetyl-D-galactosamine (GalNAc) (β1→4 linked)
D-glucuronic acid (GlcA) (β1→78 linked)
Source
Chemical synthesis
Impurities
No visible impurities to the naked eye.
Solubility
This product is soluble in most organic solvents, such as DCM, DMF, DMSO, and THF, and exhibits excellent solubility in water.
Identity
Confirmed by NMR.
Applications
Chondroitin sulfate-tetrazine can be used for its potential to engineer carboxylated derivatives for ionic crosslinking experiments.
