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WNK463, Purity ≥98%
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Cat. No.: X24-09-YM866

WNK463, Purity ≥98%

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Synonym: 2012607-27-9; WNK-463; WNK 463; N-Tert-butyl-3-[1-[5-[5-(trifluoromethyl)-1,3,4-oxadiazol-2-yl]pyridin-2-yl]piperidin-4-yl]imidazole-4-carboxamide

  • CAS Number: 2012607-27-9
  • Compound CID: 121487936
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Product Size
1 mg; 5 mg; 10 mg; 20 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
WNK463, soluble in DMSO and ethanol and insoluble in water, is an orally bioavailable pan-WNK-kinase inhibitor. The molecular weight of the compound is 463.46, and its molecular formula is C21H24F3N7O2.
Molecular Weight
463.46
Molecular Formula
C21H24F3N7O2
Form
Lyophilized powder
Purity
≥98%
Impurities
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.
Solubility
In vitro: DMSO: 81 mg/mL (174.77 mM); Water: insoluble; Ethanol: 81 mg/mL (174.77 mM); In vivo: 5% DMSO + 30% PEG 300 + 5% Tween 80 + ddH2O, 7 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
WNK463 can be studied extensively for its potential therapeutic applications in the treatment of hypertension and related cardiovascular conditions by modulating renal function and sodium transport.
Publications
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