Cat. No.: X24-05-ZQ094
PI3K inhibitor GDC-0326, Purity ≥98%
Synonym: 1282514-88-8; GDC0326; GDC 0326; PI3K inhibitor
- CAS Number: 1282514-88-8
- Compound CID: 58204997
Product Size
5 mg; 10 mg; 50 mg; 100 mg
Properties
Description
GDC-0326, soluble in DMSO and ethanol and insoluble in water, is a potent compound that inhibits PI3 kinase activity. It targets PI3Kα, PI3Kβ, PI3Kδ, and PI3Kγ.
Molecular Formula
C19H22N6O3
Targets
PI3Kα: 0.2 nM (Ki); PI3Kβ: 26.6 nM (Ki); PI3Kδ: 4 nM (Ki); PI3Kγ: 10.2 nM (Ki)
Solubility
DMSO: 72 mg/mL (188.27 mM); Water: Insoluble; Ethanol: 18 mg/mL (47.07 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
GDC-0326 can be employed to study PI3Kα inhibition and its effects on cancer cell proliferation and survival.
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