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PI3K inhibitor GDC-0980, Purity ≥98%
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Cat. No.: X24-05-ZQ019

PI3K inhibitor GDC-0980, Purity ≥98%

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Synonym: 1032754-93-0; GDC0980; Apitolisib; RG7422; PI3K inhibitor

  • CAS Number: 1032754-93-0
  • Compound CID: 25254071
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Product Size
5 mg; 10 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
GDC-0980, soluble in DMSO and insoluble in ethanol and water, is a potent compound that inhibits PI3 kinase activity. It targets mTOR, p110α, p110β, p110δ, and p110γ.
Molecular Weight
498.6
Molecular Formula
C23H30N8O3S
Targets
mTOR: 17 nM (Ki app); p110α: 5 nM; p110β: 27 nM; p110δ: 7 nM; p110γ: 14 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 20 mg/mL (40.11 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
GDC-0980 can be used to study dual PI3K/mTOR inhibition in cancer cells.
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