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PI3K inhibitor dactolisib tosylate, Purity ≥98%
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Cat. No.: X24-05-ZQ011

PI3K inhibitor dactolisib tosylate, Purity ≥98%

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Synonym: 1028385-32-1; BEZ235 (Tosylate); NVP-BEZ 235 (Tosylate); PI3K inhibitor

  • CAS Number: 1028385-32-1
  • Compound CID: 49803145
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Product Size
50 mg; 100 mg; 500 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Dactolisib tosylate is a potent compound that inhibits PI3 kinase activity. It targets Autophagy, mTOR, mTORC1, mTORC2, p110α, p110α-E545K, p110α-H1047R, p110β, p110δ, and p110γ.
Molecular Weight
641.74
Molecular Formula
C37H31N5O4S
Targets
Autophagy; mTOR: 20.7 nM; mTORC1; mTORC2; p110α: 4 nM; p110α-E545K: 5.7 nM; p110α-H1047R: 4.6 nM; p110β: 75 nM; p110δ: 7 nM; p110γ: 5 nM
Form
Lyophilized powder
Purity
≥98%
Identity
Confirmed by NMR/HPLC/MS.
Applications
Dactolisib tosylate can be used to study the dual inhibition of PI3K/mTOR in cancer and other proliferative disorders.
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