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Cat. No.: XGB1033
2-Aminoacridone
Synonym: 2-Amino-9(10H)-acridinone,2-amino-10H-acridin-9-one,AMAC
- MDL: MFCD00037397
- CAS Number: 27918-14-5
- PubChem Substance ID: 329748253
- REAXYS Number: 172520
- NACRES: NA.32
Properties
Molecular Weight
210.23
Empirical Formula
C13H10N2O
Purity
BioReagent, suitable for fluorescence, ≥98.0% (HPLC)
Solubility
DMF: soluble
Applications
2-Aminoacridone is a highly fluorescent aromatic, which contains a primary amine group that reacts with an aldehyde group at the reducing end of a carbohydrate and is reduced to a stable amine derivative by sodium borohydride (NaBH4). Picomolar levels of glycan compounds can be detected using this fluorophore. The resulting derivatzed compounds can be separated by reverse-phase HPLC and detected by positive-ion electrospray MS . An intense fluorescent, hydrophobic probe that is stable over a wide pH range is useful in the derivatization of glycans to allow for the analysis of complex oligosaccharides using micellar electrokinetic capillary chromatography and reverse- and normal-phase chromatography coupled with mass spectroscopy to determine relative concentrations and structural identity of individual oligosaccharides >. The λ excitation and λ emission are 425 nm and 532 nm, respectively.
Fluorescent label for glycans and saccharides.
Safety Information
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
WGK Germany
WGK 3
Hazard Statements
H315 - H319 - H335
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