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7-Ethyl-10-hydroxycamptothecin liposome

Inquiry

Cat. No.: X26-05-ZQ2174

7-Ethyl-10-hydroxycamptothecin liposome

Name: 7-Ethyl-10-hydroxycamptothecin liposome
SKU: X26-05-ZQ2174

Inquiry

Synonym: 7-Ethyl-10-hydroxycamptothecin LPs; SN-38 liposomes; SN-38-loaded liposomal nanoparticles

Product Size

100 mg; 250 mg; 500 mg; 1 g; 5 g

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

This formulation features 7-ethyl-10-hydroxycamptothecin liposomes engineered to encapsulate a poorly water-soluble topoisomerase I inhibitor within a stable vesicle matrix. The structural matrix incorporates the hydrophobic camptothecin derivative 7-ethyl-10-hydroxycamptothecin (commonly known as SN-38) directly within the lipophilic hydrocarbon tail core and interfacial zones of a high-purity phospholipid bilayer framework, utilizing an optimized cholesterol ratio to maximize structural stability. This configuration isolates the active lactone ring from premature aqueous hydrolysis and controls passive cargo crystallization, maintaining high chemical and colloidal stability under ambient laboratory conditions.

Source

Custom synthesis

Functional Group

7-Ethyl-10-hydroxycamptothecin (SN-38)

Form

Solid or powder

Purity

≥95%

Impurities

No visible impurities to the naked eye.

Identity

HPLC/MS/NMR

Publications

Publications (0)

Publications

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Publications

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