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7-Ethyl-10-hydroxycamptothecin (SN-38) proliposomes
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Cat. No.: X26-05-ZQ1656

7-Ethyl-10-hydroxycamptothecin (SN-38) proliposomes

Synonym: 7-Ethyl-10-hydroxycamptothecin PLs; SN-38 proliposomes; SN-38 dry powder liposomes; SN-38 PLs

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Product Size
100 mg; 250 mg; 500 mg; 1 g; 5 g
Price
Datasheet
MSDS
Properties
Description
This product features 7-ethyl-10-hydroxycamptothecin proliposomes [7-Ethyl-10-hydroxycamptothecin (SN-38) proliposomes] engineered as a dry, granular precursor system for the rapid generation of liposomes. The solid matrix consists of a high-surface-area carrier carbohydrate or polyol framework coated with a uniform film of dehydrated high-purity phospholipids, cholesterol, and the highly hydrophobic camptothecin derivative SN-38 (7-ethyl-10-hydroxycamptothecin). Upon hydration in an aqueous laboratory environment, this dry composition spontaneously undergoes structural remodeling, forming a self-assembled suspension of sub-micron vesicles that encapsulate the camptothecin cargo within their lipophilic hydrocarbon domains. This configuration maintains the chemical integrity of the active ingredient and prevents hydrolytic degradation during dry storage.
Source
Custom synthesis
Functional Group
7-Ethyl-10-hydroxycamptothecin
Form
Solid or powder
Purity
≥95%
Impurities
No visible impurities to the naked eye.
Identity
HPLC/MS/NMR
Publications
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