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Akt inhibitor Afuresertib HCl, Purity ≥98%
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Cat. No.: X24-05-ZQ183

Akt inhibitor Afuresertib HCl, Purity ≥98%

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Synonym: 1047645-82-8; GSK2110183; GSK 2110183; Akt inhibitor

  • CAS Number: 1047645-82-8
  • Compound CID: 46843056
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Product Size
5 mg; 10 mg; 25 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Afuresertib HCl inhibits the phosphorylation of Akt with anti-inflammatory properties. It targets Akt1, Akt1 E17K mutant, Akt2, Akt3, PKCη, PKCθ, PKC-βI, and ROCK.
Molecular Weight
463.78
Molecular Formula
C18H18Cl3FN4OS
Targets
Akt1: 0.08 nM (Ki); Akt1 E17K mutant: 0.2 nM; Akt2: 2 nM (Ki); Akt3: 2.6 nM (Ki); PKCη: 210 nM; PKCθ: 510 nM; PKC-βI: 430 nM; ROCK: 100 nM
Form
Lyophilized powder
Purity
≥98%
Identity
Confirmed by NMR/HPLC/MS.
Applications
Afuresertib HCl can be used in studies to understand its role in modulating Akt-related cancer progression.
Publications
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