BAY1125976, soluble in DMSO and insoluble in ethanol and water, inhibits the phosphorylation of Akt with anti-inflammatory properties. It targets Akt1, Akt2, and Akt3.
Molecular Weight
383.45
Molecular Formula
C23H21N5O
Targets
Akt1: 5.2 nM (IC50, at 10 μM ATP); Akt2: 18 nM (IC50, at 10 μM ATP); Akt3: 427 nM (IC50, at 10 μM ATP)
BAY1125976 is used to explore the inhibition of Akt and its effects on cancer cell proliferation.
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