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ALK inhibitor ALK-IN-1, Purity ≥98%
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Cat. No.: X24-06-ZQ295

ALK inhibitor ALK-IN-1, Purity ≥98%

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Synonym: 1197958-12-5; ALK inhibitor; AP-26113

  • MDL: MFCD23704187
  • CAS Number: 1197958-12-5
  • Compound CID: 57390074
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Product Size
5 mg; 10 mg; 25 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
ALK-IN-1, soluble in DMSO and ethanol and insoluble in water, is a protein tyrosine kinase inhibitor that has shown potent biochemical activity against ALK. It targets FER, ROS/ROS1, Abl1, ALK, ARK5, Aurora A, BLK, BRK, BRSK1, BRSK2, BTK.
Molecular Weight
529.01
Molecular Formula
C26H34ClN6O2P
Targets
FER: 1.3 nM; ROS/ROS1: 1.9 nM; Abl1: 500 nM; ALK: 0.62 nM; ARK5: 47 nM; AuroraA: 146 nM; BLK: 136 nM; BRK: 4.1 nM; BRSK1: 338 nM; BRSK2: 125 nM; BTK: 673 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 40 mg/mL (75.61 mM); Water: Insoluble; Ethanol: 93 mg/mL (175.8 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
ALK-IN-1 is used to investigate ALK inhibition, which plays a critical role in developing treatments for ALK-positive cancers.
Publications
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