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ALK inhibitor CH5424802, Purity ≥98%
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Cat. No.: X24-06-ZQ305

ALK inhibitor CH5424802, Purity ≥98%

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Synonym: 1256580-46-7; ALK inhibitor; CH-5424802

  • MDL: MFCD19440988
  • CAS Number: 1256580-46-7
  • Compound CID: 49806720
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Product Size
5 mg; 10 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
CH5424802, soluble in warmed DMSO and insoluble in water and ethanol, is a protein tyrosine kinase inhibitor that has shown potent biochemical activity against ALK. It targets ALK, ALK (R1275Q), Abl, Akt1, Akt2, Akt3, ALK(F1174L), AuroraA, CDK1, CDK2, and EGFR.
Molecular Weight
482.6
Molecular Formula
C30H34N4O2
Targets
ALK: 1.9 nM; ALK (R1275Q): 3.5 nM; Abl: >5 μM; Akt1: >5 μM; Akt2: >5 μM; Akt3: >5 μM; ALK (F1174L): 1 nM; AuroraA: >5 μM; CDK1: >5 μM; CDK2: >5 μM; EGFR: >5 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
Warmed DMSO: 0.5 mg/mL (1.03 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
CH5424802 (also known as alectinib) is a selective inhibitor of ALK, critical for studying treatments targeting ALK-positive NSCLC.
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